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Qualifications: Diabetic issues Mellitus (DM) triggers an extreme response of absolutely free-radicals. It boosts reactive oxygen species and decreases antioxidants status and also the β cell destruction. Clear kefir was employed for DM therapies, nonetheless it restricted biomolecular exploration of its bioactive roles. Research aimed to analyze the results of very clear kefir within the biomolecular character with the glycemic status of T2DM in Bandung. Strategies: The randomized pretest-posttest Manage team was performed by 106 T2DM clients. Investigation was completed in numerous hospitals in Bandung and Cimahi, West Java from 2012–2013. Samples had been divided randomly into a few groups: (one) T2DM with HbA1c < 7 was fed a typical diet program, supplemented with two hundred ml/working day of apparent kefir, (2) T2DM with HbA1c > seven fed standard eating plan and supplemented 200 ml/working day by clear kefir, (3) T2DM with HbA1c was fed a normal diet to be a Handle team.